Article
Association between a genetic variant in the serotonin transporter gene (SLC6A4) and suicidal behavior in patients with schizophrenia.
Behavioral and brain functions : BBF - 17 May 2012
Lindholm Carlström Eva, Saetre Peter, Rosengren Anders, Thygesen Johan H, Djurovic Srdjan, Melle Ingrid, Andreassen Ole A, Werge Thomas, Agartz Ingrid, Hall Håkan, Terenius Lars, Jönsson Erik G
Abstract excerpt
BACKGROUND: The serotonin (5-hydroxytryptamin; 5-HT) system has a central role in the circuitry of cognition and emotions. Multiple lines of evidence suggest that genetic variation in the serotonin transporter gene (SLC6A4; 5-HTT) is associated with schizophrenia and suicidal behavior. In this study, we wanted to elucidate whether SLC6A4 variations is involved in attempted suicide among patients with...
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