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Article

A genome-wide study reveals copy number variants exclusive to childhood obesity cases.

American journal of human genetics - 12 Nov 2010

Glessner Joseph T, Bradfield Jonathan P, Wang Kai, Takahashi Nagahide, Zhang Haitao, Sleiman Patrick M, Mentch Frank D, Kim Cecilia E, Hou Cuiping, Thomas Kelly A, Garris Maria L, Deliard Sandra, Frackelton Edward C, Otieno F George, Zhao Jianhua, Chiavacci Rosetta M, Li Mingyao, Buxbaum Joseph D, Berkowitz Robert I, Hakonarson Hakon, Grant Struan F A

Abstract excerpt

The prevalence of obesity in children and adults in the United States has increased dramatically over the past decade. Genomic copy number variations (CNVs) have been strongly implicated in subjects with extreme obesity and coexisting developmental delay. To complement these previous studies, we addressed CNVs in common childhood obesity by examining children with a BMI in the upper 5(th) percentile but excluding...

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Black or African American
Black People
Child
DNA Copy Number Variations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Predisposition to Disease

Genome-Wide Association Study

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Open in PubMed Open full text

Identifiers

PMID: 20950786
DOI: 10.1016/j.ajhg.2010.09.014
PMCID: PMC2978976

Genes

ABCB5
ARL15
EDIL3
EPHA6
FOXP2
TBCA
ZPLD1

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