Article
Donor age and ABCB1 1199G>A genetic polymorphism are independent factors affecting long-term renal function after kidney transplantation.
The Journal of surgical research - 1 Dec 2012
De Meyer Martine, Haufroid Vincent, Elens Laure, Fusaro Fabio, Patrono Damiano, De Pauw Luc, Kanaan Nada, Goffin Eric, Mourad Michel
Abstract excerpt
BACKGROUND: In renal tubular cells, cytochrome P4503A enzyme and adenosine triphosphate-binding cassette transporter activities result in intracellular drug or metabolite exposure variability, depending on genetic polymorphisms. Our aim was to establish whether long-term renal function is affecte...
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