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Article

Donor ABCB1 variant associates with increased risk for kidney allograft failure.

Journal of the American Society of Nephrology : JASN - 1 Nov 2012

Moore Jason, McKnight Amy Jayne, Döhler Bernd, Simmonds Matthew J, Courtney Aisling E, Brand Oliver J, Briggs David, Ball Simon, Cockwell Paul, Patterson Christopher C, Maxwell Alexander P, Gough Stephen C L, Opelz Gerhard, Borrows Richard

Abstract excerpt

The impact of variation within genes responsible for the disposition and metabolism of calcineurin inhibitors (CNIs) on clinical outcomes in kidney transplantation is not well understood. Furthermore, the potential influence of donor, rather than recipient, genotypes on clinical endpoints is unkn...

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Calcineurin Inhibitors

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Source

Open in PubMed Open full text

Identifiers

PMID: 23064017
DOI: 10.1681/ASN.2012030260
PMCID: PMC3482733

Genes

ABCB1
PPIA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23064017-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Effect of CYP3A and ABCB1 single nucleotide polymorphisms on the pharmacokinetics and pharmacodynamics of calcineurin inhibitors: Part II.Semantic proximity Read ↗

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