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Article

Extreme population differences across Neuregulin 1 gene, with implications for association studies.

Molecular psychiatry - 1 Jan 2006

Gardner M, González-Neira A, Lao O, Calafell F, Bertranpetit J, Comas D

Abstract excerpt

Neuregulin 1 (NRG1) is one of the most exciting candidate genes for schizophrenia in recent years since its first association with the disease in an Icelandic population. Since then, many association studies have analysed allele and haplotype frequencies in distinct populations yielding varying r...

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Source

Identifiers

PMID: 16189508
DOI: 10.1038/sj.mp.4001749

Genes

NRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16189508-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Extreme population differences across Neuregulin 1 gene, with implications for association studies.PMID 16189508Read ↗

Support for genetic variation in neuregulin 1 and susceptibility to schizophrenia.Semantic proximity Read ↗

Association of neuregulin 1 with schizophrenia confirmed in a Scottish population.Semantic proximity Read ↗

Identification of a novel neuregulin 1 at-risk haplotype in Han schizophrenia Chinese patients, but no association with the Icelandic/Scottish risk haplotype.Semantic proximity Read ↗

Meta-analysis shows strong positive association of the neuregulin 1 (NRG1) gene with schizophrenia.Semantic proximity Read ↗

Association of Neuregulin 1 with schizophrenia and bipolar disorder in a second cohort from the Scottish population.Semantic proximity Read ↗

Meta-analysis reveals associations between genetic variation in the 5' and 3' regions of Neuregulin-1 and schizophrenia.Semantic proximity Read ↗

Support for NRG1 as a susceptibility factor for schizophrenia in a northern Swedish isolated population.Semantic proximity Read ↗

No significant association of the 5' end of neuregulin 1 and schizophrenia in a large Danish sample.Semantic proximity Read ↗

Extreme individual marker F(ST )values do not imply population-specific selection in humans: the NRG1 example.Semantic proximity Read ↗

Family-based association study of neuregulin-1 gene and psychosis in a Spanish sample.Semantic proximity Read ↗

Supportive evidence for neuregulin 1 as a susceptibility gene for schizophrenia in a Japanese population.Semantic proximity Read ↗

Support for involvement of neuregulin 1 in schizophrenia pathophysiology.Semantic proximity Read ↗

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