Article
NMDA receptor genotypes associated with the vulnerability to develop dyskinesia.
Translational psychiatry - 10 Jan 2012
Ivanova S A, Loonen A J M, Pechlivanoglou P, Freidin M B, Al Hadithy A F Y, Rudikov E V, Zhukova I A, Govorin N V, Sorokina V A, Fedorenko O Y, Alifirova V M, Semke A V, Brouwers J R B J, Wilffert B
Abstract excerpt
Dyskinesias are involuntary muscle movements that occur spontaneously in Huntington's disease (HD) and after long-term treatments for Parkinson's disease (levodopa-induced dyskinesia; LID) or for schizophrenia (tardive dyskinesia, TD). Previous studies suggested that dyskinesias in these three conditions originate from different neuronal pathways that converge on overstimulation of the motor cortex. We...
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