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Article

Experimental basis for the putative role of GluR6/kainate glutamate receptor subunit in Huntington's disease natural history.

Neurobiology of disease - 1 Apr 2004

Diguet Elsa, Fernagut Pierre-Olivier, Normand Elisabeth, Centelles Laurie, Mulle Christophe, Tison François

Abstract excerpt

Age of onset of Huntington's disease (HD) statistically correlates with the length of expanded CAG repeats in the IT15 gene. However, other factors such as polymorphism in the 3' untranslated region of the GluR6 kainate receptor gene subunit may contribute to variability in the age at onset. To investigate this issue, we studied the motor disorder and related striatal damage induced by 3-nitropropionic acid...

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Identifiers

PMID: 15056475
DOI: 10.1016/j.nbd.2003.12.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Experimental basis for the putative role of GluR6/kainate glutamate receptor subunit in Huntington's disease natural history.PMID 15056475Read ↗

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