Article
Longitudinal Monitoring of Circulating Tumor DNA From Plasma in Patients With Curative Resected Stages I to IIIA EGFR-Mutant Non-Small Cell Lung Cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Sept 2023
Jung Hyun-Ae, Ku Bo Mi, Kim Yeon Jeong, Park Sehhoon, Sun Jong-Mu, Lee Se-Hoon, Ahn Jin Seok, Cho Jong Ho, Kim Hong Kwan, Choi Yong Soo, Choi Yoon-La, Shin Sun Hye, Jeong Byeong-Ho, Um Sang-Won, Kim Hojoong, Kim Kyunga, Ahn Myung-Ju, Kim Jingook
Abstract excerpt
INTRODUCTION: For patients with early stage EGFR-mutant-positive (EGFR-M+) NSCLC, curative surgery followed by adjuvant chemotherapy is considered the standard of care. This study evaluated the feasibility and efficacy of longitudinal monitoring of circulating tumor DNA (ctDNA) as a valuable biomarker for early detection of minimal residual disease (MRD) and provides identification of the group at high risk for...
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