Article
Induction of beta-lactamases: in vitro phenomena and clinical relevance.
The Journal of international medical research - 1 Jan 1990
Wiedemann B, Peter K
Abstract excerpt
An in vitro model was used to stimulate the plasma concentration-time curves for cefotaxime and cefoxitin as they would appear during treatment of patients with infections due to Enterobacter cloacae and Proteus vulgaris. The data showed that the induction of the chromosomally mediated beta-lacta...
Topics
- Cefotaxime
- Cefoxitin
- Enterobacter
- Enzyme Induction
- Humans
- Mutation
- Proteus vulgaris
- Time Factors
- beta-Lactamases