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Article

Induction of beta-lactamases: in vitro phenomena and clinical relevance.

The Journal of international medical research - 1 Jan 1990

Wiedemann B, Peter K

Abstract excerpt

An in vitro model was used to stimulate the plasma concentration-time curves for cefotaxime and cefoxitin as they would appear during treatment of patients with infections due to Enterobacter cloacae and Proteus vulgaris. The data showed that the induction of the chromosomally mediated beta-lactamase took place in both bacteria but that it had little or no effect on the bacterial kill. It is concluded that...

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PMID: 2282970

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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