Article
Acute behavioral effects of nicotine in male and female HINT1 knockout mice.
Genes, brain, and behavior - 1 Nov 2012
Jackson K J, Wang J B, Barbier E, Chen X, Damaj M I
Abstract excerpt
Human genetic association and brain expression studies, and mouse behavioral and molecular studies implicate a role for the histidine triad nucleotide-binding protein 1 (HINT1) in schizophrenia, bipolar disorder, depression and anxiety. The high comorbidity between smoking and psychiatric disorders, schizophrenia in particular, is well established. Associations with schizophrenia and HINT1 are also sex specific,...
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