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Article

Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice.

PloS one - 1 Jan 2012

Long Leonora E, Chesworth Rose, Huang Xu-Feng, Wong Alexander, Spiro Adena, McGregor Iain S, Arnold Jonathon C, Karl Tim

Abstract excerpt

The cannabis constituent cannabidiol (CBD) possesses anxiolytic and antipsychotic properties. We have previously shown that transmembrane domain neuregulin 1 mutant (Nrg1 TM HET) mice display altered neurobehavioural responses to the main psychoactive constituent of cannabis, Δ(9)-tetrahydrocannabinol. Here we investigated whether Nrg1 TM HET mice respond differently to CBD and whether CBD reverses...

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Identifiers

PMID: 22509273
DOI: 10.1371/journal.pone.0034129
PMCID: PMC3317922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Distinct neurobehavioural effects of cannabidiol in transmembrane domain neuregulin 1 mutant mice.PMID 22509273Read ↗

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Transmembrane domain Nrg1 mutant mice show altered susceptibility to the neurobehavioural actions of repeated THC exposure in adolescence.Semantic proximity Read ↗

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