Article
Autophagy and Its Comprehensive Impact on ALS.
The International journal of neuroscience - 1 Dec 2012
Song Cheng-yuan, Guo Ji-feng, Liu Yuan, Tang Bei-sha
Abstract excerpt
Autophagy is a degradative modality that involves intracellular elimination of proteins and organelles by lysosomes. It is a conservative process and plays a crucial role in cell growth and development, and keeping cellular homeostasis especially under stress-induced situations. Recently, increasing evidence suggests that autophagic alternations may contribute to amyotrophic lateral sclerosis (ALS) as one of...
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