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Article

Autophagy Dysregulation in Amyotrophic Lateral Sclerosis

8 Dec 2011

Abstract excerpt

Autophagy is an intracellular lysosomal degradation process, which plays an important role in cell growth and development, and keeping cellular homeostasis in all eukaryotes. Autophagy has multiple physiological functions, including protein degradation, organelle turnover and response to stress. Emerging evidences support the notion that dysregulation of autophagy might be critical for pathogenesis of amyotrophic...

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PMID: 22150926
DOI: 10.1111/j.1750-3639.2011.00546.x

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