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Article

Sex-specific differences in effect size estimates at established complex trait loci.

International journal of epidemiology - 1 Oct 2012

Orozco Gisela, Ioannidis John P A, Morris Andrew, Zeggini Eleftheria

Abstract excerpt

BACKGROUND: Genetic differences between men and women may contribute to sex differences in prevalence and progression of many common complex diseases. Using the WTCCC GWAS, we analysed whether there are sex-specific differences in effect size estimates at 142 established loci for seven complex diseases: rheumatoid arthritis, type 1 diabetes (T1D), Crohn's disease, type 2 diabetes (T2D), hypertension, coronary...

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PMID: 22825589
DOI: 10.1093/ije/dys104
PMCID: PMC3465768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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