Article
Functional study of risk loci of stem cell-associated gene lin-28B and associations with disease survival outcomes in epithelial ovarian cancer.
Carcinogenesis - 1 Nov 2012
Lu Lingeng, Katsaros Dionyssios, Mayne Susan T, Risch Harvey A, Benedetto Chiara, Canuto Emilie Marion, Yu Herbert
Abstract excerpt
Several single-nucleotide polymorphisms (SNPs) of the stem cell-associated gene lin-28B have been identified in association with ovarian cancer and ovarian cancer-related risk factors. However, whether these SNPs are functional or might be potential biomarkers for ovarian cancer prognosis remains unknown. The purposes of this study were to investigate the functional relevance of the identified lin-28B SNPs, as...
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