Article
Polymorphisms at the microRNA binding-site of the stem cell marker gene CD133 modify susceptibility to and survival of gastric cancer.
Molecular carcinogenesis - 1 Jun 2015
Wang Qiming, Liu Hongliang, Xiong Huihua, Liu Zhensheng, Wang Li-E, Qian Ji, Muddasani Ramya, Lu Victoria, Tan Dongfeng, Ajani Jaffer A, Wei Qingyi
Abstract excerpt
CD133 is one of the most common stem cell markers, and functional single nucleotide polymorphisms (SNPs) of CD133 may modulate its gene functions and thus cancer risk and patient survival. We hypothesized that potentially functional CD133 SNPs are associated with gastric cancer (GC) risk and survival. To test this hypothesis, we conducted a case-control study of 371 GC patients and 313 cancer-free controls...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
