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Article

Rs1347093 regulates microRNA-216/-217 expression and is associated with pancreatic cancer risk.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Dec 2024

Huang Hsin-Hung, Shiu Tzu-Yue, Chan De-Chuan, Chang Chao-Feng, Lin Hsuan-Hwai, Lin Jung-Chun, Chen Peng-Jen, Shih Yu-Lueng, Chang Wei-Kuo, Hsieh Tsai-Yuan

Abstract excerpt

BACKGROUND: Single nucleotide polymorphism (SNP) rs1347093 shows statistically significant association with lung cancer risk, but there is no further rs1347093 expression quantitative trait loci (eQTL) effect information. SNP rs1347093 is located in microRNA-216/-217 (miR-216/-217) locus. In addition, miR-216/-217 have pancreas-enriched expressions. In this study, we examined a potential miR-216/-217 promoter...

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Share to Cell Line, Tumor
Share to Gene Expression Regulation, Neoplastic
Share to Genetic Predisposition to Disease
Share to MicroRNAs
Share to Pancreatic Neoplasms
Share to Polymorphism, Single Nucleotide
Share to Promoter Regions, Genetic

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Identifiers

PMID: 39500645
DOI: 10.1016/j.pan.2024.10.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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