Article
Cutaneous reactions induced by oxcarbazepine in Southern Han Chinese: incidence, features, risk factors and relation to HLA-B alleles.
Seizure - 1 Oct 2012
He Na, Min Fu-Li, Shi Yi-Wu, Guo Jing, Liu Xiao-Rong, Li Bing-Mei, Zhou Jin-Hua, Ou Yang-Mei, Liao Jian-Xiang, Liao Wei-Ping
Abstract excerpt
PURPOSE: Oxcarbazepine (OXC) is a promising alternative for patients who cannot tolerate carbamazepine. Recently, however, it has been reported that OXC-induced cutaneous adverse drug reactions (cADRs) are prevalent and may lead to drug discontinuation. Additionally, these reactions are thought to be associated with HLA-B*1502. This study aims to investigate the incidence, features and risk factors of OXC-cADRs,...
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