Article
Pilot association study of oxcarbazepine-induced mild cutaneous adverse reactions with HLA-B*1502 allele in Chinese Han population.
Seizure - 1 Mar 2011
Hu Fa-yun, Wu Xin-tong, An Dong-mei, Yan Bo, Stefan Hermann, Zhou Dong
Abstract excerpt
BACKGROUND: Recent study demonstrated that HLA-B*1502 was a common risk allele in aromatic antiepileptic drugs (AEDs) induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Han Chinese. However, the association of AEDs-induced mild maculopapular eruption (MPE) with HLA-B*1502 remains unclear until recently. In the present study, we conducted a pilot study to detect a possible association of...
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