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Article

Abnormal temporal lobe white matter as a biomarker for genetic risk of bipolar disorder.

Biological psychiatry - 15 Jan 2013

Mahon Katie, Burdick Katherine E, Ikuta Toshikazu, Braga Raphael J, Gruner Patricia, Malhotra Anil K, Szeszko Philip R

Abstract excerpt

BACKGROUND: Brain white matter (WM) abnormalities have been hypothesized to play an important role in the neurobiology of bipolar disorder (BD). The nature of these abnormalities is not well-characterized, however, and it is unknown whether they occur after disease onset or represent potential markers of genetic risk. METHODS: We examined WM integrity (assessed via fractional anisotropy [FA]) with diffusion...

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Identifiers

PMID: 23036958
DOI: 10.1016/j.biopsych.2012.07.033
PMCID: PMC3760506

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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