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Article

Abnormalities in left inferior frontal gyral thickness and parahippocampal gyral volume in young people at high genetic risk for bipolar disorder.

Psychological medicine - 1 Jul 2016

Roberts G, Lenroot R, Frankland A, Yeung P K, Gale N, Wright A, Lau P, Levy F, Wen W, Mitchell P B

Abstract excerpt

BACKGROUND: Fronto-limbic structural brain abnormalities have been reported in patients with bipolar disorder (BD), but findings in individuals at increased genetic risk of developing BD have been inconsistent. We conducted a study in adolescents and young adults (12-30 years) comparing measures of fronto-limbic cortical and subcortical brain structure between individuals at increased familial risk of BD (at...

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PMID: 27067698
DOI: 10.1017/S0033291716000507

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