Article
The complement system in pediatric systemic lupus erythematosus, atypical hemolytic uremic syndrome, and complocentric membranoglomerulopathies.
Current opinion in rheumatology - 1 Sept 2012
Ornstein Bradley W, Atkinson John P, Densen Peter
Abstract excerpt
PURPOSE OF REVIEW: This review summarizes the recent advances in complement biology and the evolving understanding of these contributions to the pathophysiology and treatment of predominantly pediatric disease syndromes. RECENT FINDINGS: Identification of lupus patients with complete deficiencies of one of the plasma complement proteins enabled the field to move beyond the notion of complement as a laboratory...
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