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Article

Mutation analysis of NF-κB signal pathway-related genes in ocular MALT lymphoma.

International journal of clinical and experimental pathology - 1 Jan 2012

Liu Fang, Karube Kennosuke, Kato Harumi, Arita Kotaro, Yoshida Noriaki, Yamamoto Kiyoko, Tsuzuki Shinobu, Kim Wonseog, Ko Young-Hyeh, Seto Masao

Abstract excerpt

Constitutive nuclear factor-kappa B (NF-κB) activation has been reported in ocular adnexal lymphoma (OAL). TNFAIP3/A20 is a "global" inhibitor of NF-κB pathway. We have shown that OAL has preferential loss of the 6q23.3 region where TNFAIP3/A20 exist, which is suggested to involve in lymphomagenesis of OAL. The mechanisms causing NF-κB activity in OAL remain elusive. Recently, NF-κB canonical pathway genes...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, B-Cell, Marginal Zone

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Source

Open in PubMed Open full text

Identifiers

PMID: 22808296
PMCID: PMC3396059

Genes

TNFAIP3
CARD11
MYD88

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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