Article
Mu2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans.
The Journal of cell biology - 1 Dec 2008
Gu Mingyu, Schuske Kim, Watanabe Shigeki, Liu Qiang, Baum Paul, Garriga Gian, Jorgensen Erik M
Abstract excerpt
Synaptic vesicles must be recycled to sustain neurotransmission, in large part via clathrin-mediated endocytosis. Clathrin is recruited to endocytic sites on the plasma membrane by the AP2 adaptor complex. The medium subunit (micro2) of AP2 binds to cargo proteins and phosphatidylinositol-4 ,5-bi...
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