Article
KRAS mutation is present in a small subset of primary urinary bladder adenocarcinomas.
Histopathology - 1 Dec 2012
Alexander Riley E, Lopez-Beltran Antonio, Montironi Rodolfo, MacLennan Gregory T, Post Kristin M, Bilbo Sarah A, Jones Timothy D, Huang Wenbin, Rao Qiu, Sen Joyashree D, Meehan Kari, Cornwell Anita, Miravalle Leticia, Cheng Liang
Abstract excerpt
AIMS: To determine whether KRAS mutations occur in primary bladder adenocarcinoma. METHODS AND RESULTS: Twenty-six cases of primary urinary bladder adenocarcinoma were analysed. DNA was extracted from formalin-fixed, paraffin-embedded tissue and amplified with shifted termination assay technology, which recognizes wild-type or mutant target sequences and selectively extends detection primers with labelled...
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