Article
A haplotype of the CYP4F2 gene associated with myocardial infarction in Japanese men.
Molecular genetics and metabolism - 1 Mar 2009
Fu Zhenyan, Nakayama Tomohiro, Sato Naoyuki, Izumi Yoichi, Kasamaki Yuji, Shindo Atsushi, Ohta Masakatsu, Soma Masayoshi, Aoi Noriko, Sato Mikano, Ozawa Yukio, Ma Yitong, Matsumoto Koichi, Doba Nobutaka, Hinohara Shigeaki
Abstract excerpt
This study assessed associations between the CYP4F2 gene and myocardial infarction (MI), using a haplotype-based case-control study of 234 MI patients and 248 controls genotyped for 5 single-nucleotide polymorphisms (rs3093105, rs3093135, rs1558139, rs2108622, rs3093200). For men, G allele frequency of and frequency of the T-C-G haplotype were significantly higher, and frequency of the T-C-A haplotype...