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Article

Prediction of inter domain interactions in modular polyketide synthases by docking and correlated mutation analysis.

Journal of biomolecular structure & dynamics - 1 Jan 2013

Yadav Gitanjali, Anand Swadha, Mohanty Debasisa

Abstract excerpt

Polyketide synthases (PKSs) are huge multi-enzymatic protein complexes involved in the biosynthesis of one of the largest families of bioactive natural products, namely polyketides. The specificity of interactions between various catalytic domains of these megasynthases is one of the pivotal factors which control the precise order in which the extender units are joined during the biosynthetic process. Hence,...

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Identifiers

PMID: 22803697
DOI: 10.1080/07391102.2012.691342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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