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Article

An orc1 allele with a mutated APC motif is female sterile with amplification defects.

Cell cycle (Georgetown, Tex.) - 1 Aug 2012

Park So Young, Asano Maki

Abstract excerpt

The origin recognition complex 1 (ORC1) is the largest subunit of the ORC, the heteromeric hexamer. ORC1 is an essential component of the pre-replicative complex (pre-RC) that licenses eukaryote DNA replication origins. The levels of ORC1 fluctuate during the mitotic cell cycle in Drosophila as w...

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Source

Identifiers

PMID: 22801552
DOI: 10.4161/cc.21168

Genes

ORC1
APC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22801552-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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