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Article

A functional germline variant in the P53 polyadenylation signal and risk of esophageal squamous cell carcinoma.

Gene - 15 Sept 2012

Zhou Liqing, Yuan Qipeng, Yang Ming

Abstract excerpt

AIM: P53 plays a critical role in the maintenance of genomic stability as well as the control of cell growth and apoptosis. Recently, an uncommon P53 genetic variant (rs78378222) was reported to be significantly associated with multiple cancers in Caucasians in a genome-wide association study. rs78378222 locates in the 3'-untranslated region of the P53 gene, and this A-to-C polymorphism results in changes of the...

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Identifiers

PMID: 22800615
DOI: 10.1016/j.gene.2012.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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