Article
A Histone-Like Nucleoid Structuring Protein Regulates Several Virulence Traits in Burkholderia multivorans.
Applied and environmental microbiology - 25 Jun 2021
Gomes Sara C, Ferreira Mirela R, Tavares Andreia F, Silva Inês N, Becker Jörg D, Moreira Leonilde M
Abstract excerpt
Burkholderia cepacia complex bacteria comprise opportunistic pathogens causing chronic respiratory infections in cystic fibrosis (CF) patients. These microorganisms produce an exopolysaccharide named cepacian, which is considered a virulence determinant. To find genes implicated in the regulation of cepacian biosynthesis, we characterized an evolved nonmucoid variant (17616nmv) derived from the ancestor,...
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