Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive Proteome Analysis of an Apc Mouse Model Uncovers Proteins Associated with Intestinal Tumorigenesis

25 Feb 2009

Abstract excerpt

Tumor-derived proteins may occur in the circulation as a result of secretion, shedding from the cell surface, or cell turnover. We have applied an in-depth comprehensive proteomic strategy to plasma from intestinal tumor-bearing Apc mutant mice to identify proteins associated with tumor development. We used quantitative tandem mass spectrometry of fractionated mouse plasma to identify differentially expressed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Proteomics Techniques and Applications
Share to Cancer-related Molecular Pathways
Share to Digestive system and related health

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19240248
DOI: 10.1158/1940-6207.capr-08-0153

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Proteome Analysis of an Apc Mouse Model Uncovers Proteins Associated with Intestinal TumorigenesisPMID 19240248Read ↗

A Mouse to Human Search for Plasma Proteome Changes Associated with Pancreatic Tumor DevelopmentSemantic proximity Read ↗

Plasma Proteome Profiles Associated with Inflammation, Angiogenesis, and CancerSemantic proximity Read ↗

Comprehensive Proteomic Characterization of the Human Colorectal Carcinoma Reveals Signature Proteins and Perturbed PathwaysSemantic proximity Read ↗

Plasma Proteome Profiling of a Mouse Model of Breast Cancer Identifies a Set of Up-Regulated Proteins in Common with Human Breast Cancer CellsSemantic proximity Read ↗

Proteomic analyses of ECM during pancreatic ductal adenocarcinoma progression reveal different contributions by tumor and stromal cellsSemantic proximity Read ↗

Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulationSemantic proximity Read ↗

Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitisSemantic proximity Read ↗

Mass profiling of serum to distinguish mice with pancreatic cancer induced by a transgenic Kras mutation.Semantic proximity Read ↗

Proteomic analysis reveals APC-dependent post-translational modifications and identifies a novel regulator of β-catenin.Semantic proximity Read ↗

One-hit effects in cancer: altered proteome of morphologically normal colon crypts in familial adenomatous polyposis.Semantic proximity Read ↗

Lipid profiling of mouse intestinal organoids for studying APC mutations.Semantic proximity Read ↗

The proprotein convertase PC5/6 is protective against intestinal tumorigenesis: in vivo mouse modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.