Article
Association of a GSK-3β polymorphism with brain resting-state function in amnestic-type mild cognitive impairment.
Journal of Alzheimer's disease : JAD - 1 Jan 2012
Bai Feng, Shi Yongmei, Yuan Yonggui, Yue Chunxian, Zhuang Liying, Xu Xiaohui, Liu Xiaoyan, Zhang Zhijun
Abstract excerpt
The glycogen synthase kinase-3β (GSK-3β) gene has been implicated in Alzheimer's disease (AD). Polymorphisms in this gene are plausible modulators of brain function. However, little is known about the potential role of the GSK-3β rs334558 polymorphism, which has been associated with amnestic mild cognitive impairment (aMCI), which is itself associated with a high risk of AD. In this study, 43 aMCI patients and 30...
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