Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment.

doi:10.1186/1742-2094-9-263

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Article

Association of the interleukin 1 beta gene and brain spontaneous activity in amnestic mild cognitive impairment.

Journal of neuroinflammation - 1 Dec 2012

Zhuang Liying, Liu Xiaoyan, Xu Xiaohui, Yue Chunxian, Shu Hao, Bai Feng, Yu Hui, Shi Yongmei, Zhang Zhijun

Abstract excerpt

PURPOSE: The inflammatory response has been associated with the pathogenesis of Alzheimer's disease (AD). The purpose of this study is to determine whether the rs1143627 polymorphism of the interleukin-1 beta (IL-1β) gene moderates functional magnetic resonance imaging (fMRI)-measured brain regional activity in amnestic mild cognitive impairment (aMCI). METHODS: Eighty older participants (47 with aMCI and 33...

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Identifiers

PMID: 23199001
DOI: 10.1186/1742-2094-9-263
PMCID: PMC3541073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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