Article
Multivariate detection of gene-gene interactions.
Genetic epidemiology - 1 Sept 2012
Rajapakse Indika, Perlman Michael D, Martin Paul J, Hansen John A, Kooperberg Charles
Abstract excerpt
Unraveling the nature of genetic interactions is crucial to obtaining a more complete picture of complex diseases. It is thought that gene-gene interactions play an important role in the etiology of cancer, cardiovascular, and immune-mediated disease. Interactions among genes are defined as phenotypic effects that differ from those observed for independent contributions of each gene, usually detected by...
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