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Article

Ring chromosome 5 in acute myeloid leukemia defined by whole-genome single nucleotide polymorphism array.

Annals of laboratory medicine - 1 Jul 2012

Huh Jungwon, Mun Yeung Chul, Chung Wha Soon, Seong Chu Myong

Abstract excerpt

Chromosomes forming a corresponding ring cannot be clearly defined by conventional cytogenetics or FISH. Karyotypic analyses using whole-genome single nucleotide polymorphism arrays (SNP-A) may result in the identification of previously cryptic lesions and allow for more precise definition of breakpoints. We describe a case of AML with metaphase cells bearing -5, del(11)(q22), and +r. With SNP-A, a 5p-terminal...

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Share to Chromosome Deletion
Share to Chromosomes, Human, Pair 5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Karyotyping

Share to Leukemia, Myeloid, Acute

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Share to Oligonucleotide Array Sequence Analysis

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Identifiers

PMID: 22779075
DOI: 10.3343/alm.2012.32.4.307
PMCID: PMC3384815

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