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Acquired genomic copy number aberrations and survival in adult acute myelogenous leukemia

21 Aug 2010

Abstract excerpt

Genomic aberrations are of predominant importance to the biology and clinical outcome of patients with acute myelogenous leukemia (AML), and conventional karyotype-based risk classifications are routinely used in clinical decision making in AML. One of the known limitations of cytogenetic analysis is the inability to detect genomic abnormalities less than 5 Mb in size, and it is currently unclear whether...

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PMID: 20729466
DOI: 10.1182/blood-2010-01-266999

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