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Nuclear Dynamics of Histone H3 Trimethylated on Lysine 9 and/or Phosphorylated on Serine 10 in Mouse Cloned Embryos As New Markers of Reprogramming?

1 Aug 2012

Abstract excerpt

Somatic cell nuclear transfer (SCNT) is the injection of a donor nucleus into an enucleated egg. Despite the use of this technology for many years in research, it is still quite inefficient. One of the causes for this is thought to be incorrect or incomplete genome reprogramming. Embryos produced by nuclear transfer (cloned embryos) very often present abnormal epigenetic signatures and irregular chromatin...

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PMID: 22775512
DOI: 10.1089/cell.2011.0071

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Nuclear Dynamics of Histone H3 Trimethylated on Lysine 9 and/or Phosphorylated on Serine 10 in Mouse Cloned Embryos As New Markers of Reprogramming?PMID 22775512Read ↗

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