Article
Testis-specific histone variants H2AL1/2 rapidly disappear from paternal heterochromatin after fertilization.
The Journal of reproduction and development - 1 Dec 2008
Wu Fang, Caron Cécile, De Robertis Christine, Khochbin Saadi, Rousseaux Sophie
Abstract excerpt
Before fertilization, the genome packaging of male and female gametes is very different. Indeed, whereas the female haploid genome is associated with histones in a somatic-like chromatin structure, most of the male genome is tightly bound to protamines. However, it has recently been demonstrated that the pericentric heterochromatin regions of the male genome are associated with specific H2A-like histone variants,...
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