Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of His1085His INSR gene polymorphism with type 2 diabetes in South Indians.

Diabetes technology & therapeutics - 1 Aug 2012

Bodhini Dhanasekaran, Sandhiya Mohanram, Ghosh Saurabh, Majumder Partha P, Rao M R Satyanarayana, Mohan Viswanathan, Radha Venkatesan

Abstract excerpt

BACKGROUND AND OBJECTIVE: The INSR gene, which encodes the insulin receptor, is a candidate gene for type 2 diabetes (T2D). The objective of the present study was to sequence some of the crucial exons in the INSR gene such as exon 2, which encodes the insulin-binding domain of the INSR protein, and exons 17-21, which encode the protein tyrosine kinase domain for mutations/polymorphisms, and to study their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, CD
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Polymorphism, Restriction Fragment Length

Share to Receptor, Insulin

Share to White People

Source

Identifiers

PMID: 22775283
DOI: 10.1089/dia.2012.0009

Genes

INSR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of His1085His INSR gene polymorphism with type 2 diabetes in South Indians.PMID 22775283Read ↗

Association of genetic variants in INS (rs689), INSR (rs1799816) and PP1G.G (rs1799999) with type 2 diabetes (T2D): a case-control study in three ethnic groups from North-West India.Semantic proximity Read ↗

Association study of IRS1 gene polymorphisms with type 2 diabetes in south Indians.Semantic proximity Read ↗

Functional Polymorphism Located in the microRNA Binding Site of the Insulin Receptor (INSR) Gene Confers Risk for Type 2 Diabetes Mellitus in the Bangladeshi Population.Semantic proximity Read ↗

Insulin receptor gene mutations in iranian patients with type II diabetes mellitus.Semantic proximity Read ↗

Polymorphisms of exon 17 of insulin-receptor gene in pathogenesis of human disorders with insulin resistance.Semantic proximity Read ↗

Genetic variation in exon 17 of INSR is associated with insulin resistance and hyperandrogenemia among lean Indian women with polycystic ovary syndrome.Semantic proximity Read ↗

GLUT4 gene polymorphisms and their association with type 2 diabetes in south Indians.Semantic proximity Read ↗

Common RASGRP1 Gene Variants That Confer Risk of Type 2 Diabetes.Semantic proximity Read ↗

Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians.Semantic proximity Read ↗

Association between ABCC8 Ala1369Ser Polymorphism (rs757110 T/G) and Type 2 Diabetes Risk in an Iranian Population: A Case-Control Study.Semantic proximity Read ↗

Association of resistin (rs3745367) and urotensin II (rs228648 and rs2890565) gene polymorphisms with risk of type 2 diabetes mellitus in Indian population.Semantic proximity Read ↗

IRS-1 genetic polymorphism (r.2963G>A) in type 2 diabetes mellitus patients associated with insulin resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.