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Article

Polymorphisms of exon 17 of insulin-receptor gene in pathogenesis of human disorders with insulin resistance.

Biomedical and environmental sciences : BES - 1 Dec 2004

Wang Lu, Mi Jie, Zhao Xiao-Yuan, Wu Jian-Xin, Cheng Hong, Zhang Zhi-Kun, Ding Xiu-Yuan, Hou Dong-Qing, Li Hui

Abstract excerpt

OBJECTIVE: To investigate the relationship between polymorphisms of insulin-receptor (INSR) gene and insulin resistance in a population-based study in China. METHODS: Polymerase Chain Reaction (PCR) was used to the amplify Exon 17 of INSR gene and all amplified products were analyzed by direct sequencing. RESULTS: Six single-nucleotide polymorphisms (SNPs) were found at the following loci: T to TC at the locus of...

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PMID: 15745246

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INSR

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