Article
Functional Polymorphism Located in the microRNA Binding Site of the Insulin Receptor (INSR) Gene Confers Risk for Type 2 Diabetes Mellitus in the Bangladeshi Population.
Biochemical genetics - 1 Feb 2019
Parvin Mahrima, Jahan Farhana, Sarkar Pankaj Kumar, Howlader Zakir Hossain, Nabi A H M Nurun, Hosen Md Ismail
Abstract excerpt
Bangladesh has the second largest number of adults with diabetes in South Asia. Compelling evidence suggest that miRNAs contribute to the etiology of Type 2 diabetes mellitus (T2DM) by regulating many aspects of glucose homeostasis. Hence, we hypothesized that genetic polymorphisms in the diabetes-related miRNA target-binding sites could be associated with the risk of T2DM in Bangladesh. The reference Single...
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