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Association study of IRS1 gene polymorphisms with type 2 diabetes in south Indians.

Diabetes technology & therapeutics - 1 Jul 2011

Bodhini Dhanasekaran, Radha Venkatesan, Mohan Viswanathan

Abstract excerpt

BACKGROUND AND OBJECTIVES: The insulin receptor substrate-1 (IRS1) gene is a candidate gene for type 2 diabetes. The aim of this study was to investigate the association of the IRS1 gene polymorphisms Gly972Arg and Ala513Pro with type 2 diabetes in an Asian Indian population in south India. METHODS: A total of 2,148 subjects (1,187 normal glucose-tolerant [NGT] and 961 type 2 diabetes subjects) were randomly...

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Source

Identifiers

PMID: 21612394
DOI: 10.1089/dia.2011.0017

Genes

IRS1

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