Article
Polymorphisms in Fas gene is associated with HIV-related lipoatrophy in Thai patients.
AIDS research and human retroviruses - 1 Jan 2013
Likanonsakul Sirirat, Rattanatham Tippawan, Feangvad Siriluk, Uttayamakul Sumonmal, Prasithsirikul Wisit, Srisopha Somkid, Nitiyanontakij Ravee, Tengtrakulcharoen Pimrapat, Tarkowski Maciej, Riva Agostino, Nakayama Emi E, Shioda Tatsuo
Abstract excerpt
The present study aimed to evaluate the role of genetic polymorphisms in the emergence of lipoatrophy or lipodystrophy in HIV-infected patients with antiretroviral therapy (ART) in Thailand. Position 455 upstream of the Apolipoprotein C3 gene (ApoC3 T-455C, rs2854116), codon 64 of the Beta3 adrenergic receptor gene (ARβ3 Tcod64C, rs4994), and position 670 upstream of the Fas gene (Fas A-670G, rs1800682) were...
Read the complete abstract on PubMed