Article
[Establishment of a CMTM2 transgenic mouse model and the alteration of its serum testosterone level].
Zhonghua nan ke xue = National journal of andrology - 1 Jun 2012
Liu Zhen-Hua, Xiao Yun-Bei, Zhang Xiao-Wei, Xie Jing, Xu Tao, Wang Xiao-Feng
Abstract excerpt
OBJECTIVE: To establish a transgenic mouse model systemically expressing the CMTM2 gene and study the effect of the CMTM2 expression on the reproductive system of mice in vivo. METHODS: Transgenic mice were generated by microinjection of pRevTRE-CMTM2 and the genotype was detected by PCR. The expression of CMTM2 was determined by RT-PCR, Western blot and immunohistochemistry, and the serum testosterone level was...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
