Article
Overexpression of androgen-binding protein/sex hormone-binding globulin in male transgenic mice: tissue distribution and phenotypic disorders.
Biology of reproduction - 1 Jan 1997
Joseph D R, O'Brien D A, Sullivan P M, Becchis M, Tsuruta J K, Petrusz P
Abstract excerpt
The rat androgen-binding protein/sex hormone-binding globulin (ABP/SHBG) gene in transgenic mice was previously shown to be specifically expressed in the testes. This study verifies a Sertoli cell location of ABP and translation of testicular ABP mRNA in the transgenic mice by dihydrotestosterone...
Topics
- Androgen-Binding Protein
- Animals
- Blotting, Northern
- Brain Chemistry
- Dihydrotestosterone
- Electrophoresis, Gel, Two-Dimensional
- Epididymis
- Gene Expression
- Immunoblotting
- Immunohistochemistry
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Inbred DBA
- Mice, Transgenic
- Phenotype
- Proteins
- RNA, Messenger