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Article

A systematic approach to therapeutic target selection in oesophago-gastric cancer

6 Jul 2012

Abstract excerpt

OBJECTIVE: The success of personalised therapy depends on identification and inhibition of the oncogene(s) on which that tumour is dependent. We aimed to determine whether a receptor tyrosine kinase (RTK) array could be used to select the most effective therapeutic strategies in molecularly heterogeneous oesophago-gastric adenocarcinomas. DESIGN: Gene expression profiling from oesophago-gastric tumours (n=75) and...

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PMID: 22773546
DOI: 10.1136/gutjnl-2012-302039

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