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Article

p38δ MAPK phenotype: an indicator of chemotherapeutic response in oesophageal squamous cell carcinoma.

Anti-cancer drugs - 1 Jan 2015

O'Callaghan Carol, Fanning Liam J, Barry Orla P

Abstract excerpt

We recently documented p38δ differential expression and function in oesophageal squamous cell carcinoma (OESCC). This study expands upon these findings and investigates whether p38δ status in OESCC can influence response(s) to cytotoxic drugs. The antiproliferative effect of conventional cisplatin and 5-fluorouracil (CF) treatment was compared with the recently reviewed triple regime of cisplatin, 5-fluorouracil...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

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Share to Membrane Potential, Mitochondrial

Share to p38 Mitogen-Activated Protein Kinases

Source

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Identifiers

PMID: 25099621
DOI: 10.1097/CAD.0000000000000156
PMCID: PMC4243785

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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