Article
Linkage and association of successful aging to the 6q25 region in large Amish kindreds.
Age (Dordrecht, Netherlands) - 1 Aug 2013
Edwards Digna R Velez, Gilbert John R, Hicks James E, Myers Jamie L, Jiang Lan, Cummings Anna C, Guo Shengru, Gallins Paul J, Konidari Ioanna, Caywood Laura, Reinhart-Mercer Lori, Fuzzell Denise, Knebusch Claire, Laux Renee, Jackson Charles E, Pericak-Vance Margaret A, Haines Jonathan L, Scott William K
Abstract excerpt
Successful aging (SA) is a multidimensional phenotype involving living to older age with high physical function, preserved cognition, and continued social engagement. Several domains underlying SA are heritable, and identifying health-promoting polymorphisms and their interactions with the environment could provide important information regarding the health of older adults. In the present study, we examined 263...
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