Article
WDR12 and HIVEP3 are contributors to cognitive preservation in Amish SuperAgers.
Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Mar 2026
Dorfsman Daniel, Prough Michael B, Gulyayev Alex, Caywood Laura J, Clouse Jason E, Herington Sharlene D, Slifer Susan H, Adams Larry D, Laux Renee A, Song Yeunjoo E, Lynn Audrey, Fuzzell Sarada L, Hochstetler Sherri D, Miskimen Kristy, Main Leighanne R, Wang Ping, Liu Yining, Moore Noel, Ogrocki Paula, Lerner Alan J, Vance Jeffery M, Cuccaro Michael L, Haines Jonathan L, Pericak-Vance Margaret A, Scott William K
Abstract excerpt
INTRODUCTION: Cognitive SuperAgers (SAs) are individuals aged 80+ with exceptional episodic memory performance for their age, exceeding middle-aged adult norms. This study integrates family- and association-based methods to identify genetic variants associated with SAs in the Midwestern Amish population. METHODS: Eighty-three Amish SAs were grouped into 16 pedigrees for parametric and non-parametric linkage...
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