Article
Distribution of QPY and RAH haplotypes of granzyme B gene in distinct Brazilian populations.
Revista da Sociedade Brasileira de Medicina Tropical - 1 Jan 2000
Garcia Fernanda Bernadelli, Kashima Simone, Rodrigues Evandra Strazza, Silva Israel Tojal, Malta Tathiane Maistro, Nicolete Larissa Deadame de Figueiredo, Covas Dimas Tadeu, Moraes-Souza Helio
Abstract excerpt
INTRODUCTION: The cytolysis mediated by granules is one of the most important effector functions of cytotoxic T lymphocytes and natural killer cells. Recently, three single nucleotide polymorphisms (SNPs) were identified at exons 2, 3, and 5 of the granzyme B gene, resulting in a haplotype in whi...
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